Princess cruise ship in the locks of the Panama Canal - Panama Canal Cruises

Panama Canal Cruises

Set sail with Princess® – the best Panama Canal cruise line

Best Cruise Line Itineraries

13-Time Winner Recommend Magazine

We’re the number one cruise line sailing to this bucket list destination, and as awe-inspiring as it is to travel through one of Condé Nast Traveler’s 7 Cruise Wonders of the World, we’ll help you explore equally fascinating places along the way. So stretch out on a Caribbean beach, admire the pristine rainforests, stroll the cobbled streets of colonial towns and journey through the fabled Panama Canal with Princess.

View cruises From the East Coast Roundtrip Ft. Lauderdale

Roundtrip Ft. Lauderdale

From the East Coast

  • Roundtrip from Ft. Lauderdale
  • Experience a partial transit of the Panama Canal
  • Visit the pristine beaches of the Caribbean and explore the lush rainforests of Costa Rica
  • Uncover two or three of the ABC Islands (Aruba, Bonaire and Curaçao) and enjoy their vibrant culture and marine life
View cruises Ocean to Ocean Between Atlantic and Pacific Oceans

Between Atlantic & Pacific Oceans

Ocean to Ocean

  • Sail from the East Coast to the West Coast or vice versa. Cruise from Ft. Lauderdale to Los Angeles or San Francisco, or cruise from either of those two West Coast cities to Florida.
  • Ideal itinerary for those who want to experience a full transit of the Panama Canal
  • Transit all three sets of locks

Why Princess is the #1 Panama Canal Cruise Line

Meaningful travel to a bucket-list destination

A woman dressed in colorful, native attire balancing a bowl of fruit on her head

Destination immersion

We craft our Panama Canal itineraries to enrich our guests' experiences to provide the most exposure to this bucket-list destination. You'll be enchanted by Spanish and Dutch cities dating back centuries, as well as diverse tropical rainforests, white-sand beaches, dramatic volcanoes and UNESCO World Heritage Sites. And Princess provides live narration from the bridge while transiting the locks, just one reason we were voted "Best Cruise Line for Enrichment" by Cruise International.

Photo: Las Bovedas in Cartagena, Colombia

The leader in the Panama Canal

From ships custom built to sail the massive locks to immersive onboard programs and onshore adventures that inspire, Princess is the number one way to explore this epic phenomenon. We've sailed the Panama Canal since 1967 and we have more itinerary choices and departures of any cruise line in the region.

Photo: View of locks from the ship

Man leaning over the railing of a ship, holding his camera, viewing the locks of the Panama Canal
2 people riding colorful bikes on a small street next to colorful houses covered with flowers cascading from the rooftops

Abundant adventures ashore

Each voyage offers a myriad of experiences and cultures. There is something for every type of explorer in this culturally diverse region. Choose from immersive excursions such as exploring the engineering mastery of the Canal, trekking through surrounding rainforests, visiting local villages and relaxing on the pristine beaches of the Caribbean.

Photo: Old City in Cartagena, Colombia

Panama Canal Cruise Articles and Videos

Find fascinating articles with Panama Canal cruise tips for experiencing unforgettable attractions, regional cuisine, and more on both sides of this epic man-made wonder.

Travel, Airfare, & Hotels: Let Princess Get You There

Need help planning?

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Cruise deals & promotions

Find our top sales, deals, partnerships and promotions for our destinations all in one place. We run promotions throughout the year and sometimes run sweepstakes where you can win prizes!

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